منابع مشابه
Expression of biologically active bovine interleukin 7 and evaluating the activity in vitro.
AIM Interleukin 7 (IL-7) is a ϒc family cytokine involved in the homeostatic proliferation and maintenance of immune cells. In the present study, we report the expression of bovine IL-7 (bIL-7) in Escherichia coli and evaluated for its biological activity. MATERIALS AND METHODS The sequence coding for bIL-7 (mature protein) was amplified from primary bovine kidney cell culture and cloned into...
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Background: Current treatments for joint diseases are moderately successful, but unfortunately are associated with significant side effects. This study was undertaken to investigate the combination effects of IL-4 and prednisolone on tissue characteristics and production of matrix metalloproteinase-1(MMP-1) in IL-lα-treated bovine nasal cartilage (BNC) explants. Methods: BNC explants were cultu...
متن کاملInterleukin-7 and Interleukin-15 for Cancer
Interleukin 7 and 15 are considered powerful pro-inflammatory cytokines, they have the ability to destabilize chromosomes and induce tumorigenesis. Additionally, they can control malignancy proliferation by influencing the tumor microenvironment and immune system. Immunotherapy has been proposed as a treatment modality for malignancy for over a decade; the exact mechanisms of action and pathway...
متن کاملInterleukin-7 and Immunosenescence
The age of an individual is an important, independent risk factor for many of the most common diseases afflicting modern societies. Interleukin-7 (IL-7) plays a central, critical role in the homeostasis of the immune system. Recent studies support a critical role for IL-7 in the maintenance of a vigorous healthspan. We describe the role of IL-7 and its receptor in immunosenescence, the aging of...
متن کاملIL 7 R ( interleukin 7 receptor )
Review on IL7R, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
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ژورنال
عنوان ژورنال: DNA Sequence
سال: 1992
ISSN: 1042-5179
DOI: 10.3109/10425179209039696